Q90 — where it's treated in the network
Most families come to the network case manager with the karyotype already confirmed and a list of comorbidities — a heart defect, hypothyroidism or GI anomalies — that are being managed in parallel by home specialists. The case manager will help compare network clinics by cardiac and thyroid comorbidities, the age the program starts, and family logistics, then schedule the course around the main medical follow-up.
Where it is treated in our network
3 clinics in our network offer different approaches to this diagnosis.
- Shenzhen, China
Microbiota Lab
Gut-brain axis program for patients with GI symptoms (constipation, reflux, dysbiosis — in 40-50% with Down syndrome). Metagenomic 16S rRNA sequencing + personalized probiotics, nutraceuticals, FMT when indicated. As part of a multimodal plan with core rehabilitation.
Visit clinic site - Huizhou, China
Neurolife — Huizhou
Multidisciplinary early intervention program from 0 months: PT considering universal hypotonia, OT for fine motor and self-care skills, ST with oral motor exercises and Makaton sign language, sensory integration, behavioral therapy. Coordination with home cardiologist, endocrinologist, audiologist on comorbidities.
Visit clinic site - Shangrao, China
Hansi — Stem Cells
Experimental cell therapy for cognitive support: perinatal cells and exosome nasal therapy for selected Down syndrome candidates. 5-stage protocol with consultation+screening to determine response. Limited evidence base — discuss with the treating neurologist.
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What is Down Syndrome?
Down syndrome is a chromosomal disorder caused by a full or partial extra copy of chromosome 21. ICD-10 codes it as Q90 (trisomy 21). It is the most common chromosomal anomaly — affecting roughly 1 of every 700 newborns. Associated features include congenital heart defects (about 50%), hypotonia, motor and speech delay, and increased risk of thyroid and hearing pathology.
Families reach the network case manager with different needs: early intervention from the first months of life (motor stimulation, occupational therapy, speech therapy); behavioral therapy alongside accompanying features; or gut-brain-axis work for GI symptoms through the specialized Microbiota Lab center. Details on causes, symptoms, diagnostics and the rehabilitation program are in the expandable blocks below.
Frequently asked questions about Down Syndrome
At what age should early intervention begin?
Does the Microbiota gut-brain axis program help in Down syndrome?
What does Stemcells offer for cognitive support in Down syndrome?
Is inclusive schooling possible?
Other directions in this category
Other diagnoses in this category — pick the most relevant one.
Talk to a network coordinator
The coordinator reviews your documents and suggests matching clinics. We reply on Telegram and WhatsApp within an hour on workdays.